All viruses mutate. How fast depends on several factors. Viruses with an RNA genome tend to mutate faster than viruses with a DNA genome. This is because RNA viruses have less ability to fix errors when their genetic material is copied to make virus particles inside infected cells.
All viruses mutate. How fast depends on several factors. Viruses with an RNA genome tend to mutate faster than viruses with a DNA genome. This is because RNA viruses have less ability to fix errors when their genetic material is copied to make virus particles inside infected cells. So every time a virus replicates, there is the chance of a mutation occurring.
Most mutations do not change the encoded viral protein. These are considered “silent” mutations. Others do change the amino acid sequence of the encoded viral protein. However, most mutations have no functional consequence for the virus. The amino acid change does not make the virus pathogenic or not pathogenic (able to cause disease), more or less transmissible (contagious), or more or less disease causing (virulent). So, these mutations are functionally inert. Some mutations may be functionally inert to the virus but alter the ability of the infected host to recognize and eliminate the virus. These do not alter the function of the viral protein, but they do change the immunogenicity of the viral protein, which can impact virulence and transmissibility.
Mutations can result in a new “lineage” of the virus. This is not the same as a new strain. Tracking these lineages can be very useful for determining how a virus spread through communities or populations (Figure 1). For a cool interactive that shows how the various lineages of SARS-CoV-2, which causes COVID-19, spread throughout the globe visit nextstrain.org/ncov.
Mutations that alter any of the following can lead to a new strain:
Not all changes that affect immunogenicity of the viral protein affect the function of the viral protein, and not all changes that alter viral protein function affect immunogenicity (Figure 2).
Data Science and Analytics market evolves to adapt to the constantly changing economic and business environments. Our latest survey report suggests that as the overall Data Science and Analytics market evolves to adapt to the constantly changing economic and business environments, data scientists and AI practitioners should be aware of the skills and tools that the broader community is working on. A good grip in these skills will further help data science enthusiasts to get the best jobs that various industries in their data science functions are offering.
🔵 Intellipaat Data Science with Python course: https://intellipaat.com/python-for-data-science-training/In this Data Science With Python Training video, you...
The agenda of the talk included an introduction to 3D data, its applications and case studies, 3D data alignment and more.
Become a data analysis expert using the R programming language in this [data science](https://360digitmg.com/usa/data-science-using-python-and-r-programming-in-dallas "data science") certification training in Dallas, TX. You will master data...
Need a data set to practice with? Data Science Dojo has created an archive of 32 data sets for you to use to practice and improve your skills as a data scientist.