Prostate cancer (PCa) is one of most frequent malignancies in men worldwide. For example, about 190,000 new cases of prostate cancer are diagnosed in the United States annually. In addition, PCa is the second leading cause of cancer death in men. For this reason, it is crucial to accurately diagnose this disease.

The fundamental premise of the PCa diagnosis is the pathomorphological study of biopsy samples of prostate tissues and cells or postoperative materials. A pathologist can determine not only the presence and type of tumor, but also the growth and aggressiveness of malignancy and the disease prognosis. This information helps choose the optimum treatment for each patient — surgery, radiation therapy, or active monitoring.

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