A Drupal multisite for B2B of a large scale is an ultimately optimal solution, making many of your eCommerce management tasks either obsolete or much easier and faster to handle. How in particular? We can point out a couple of benefits here:

Fast global updates - no more updating every other website manually - a single codebase update covers all the interconnected Drupal resources in the network;
Reduction of resource usage - it is utterly memory-efficient to manage a bunch of sites sharing the same opcode cache;
Simple introduction of new features - a newly-added software module can be easily shared across all Drupal websites almost instantly;
Cost-savings - save on hosting per codebase, on repeated implementation services, on updates, and all other resulting managerial investments;
Extended testing - for instance, Simpletest as well as functional PHPUnit-based testing are greatly adapted to multisite principles;
Boosted resource introduction speed - one can launch a subsite based on the existing infrastructure to tackle specific issues or urgently cover controversial/trending topics in no time.
https://anyforsoft.com/blog/b2b-drupal-multisite/

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