Python throws valueerror: setting an array element with a sequence, when you are trying to create an array with the list which is not proper multi-dimensional in shape. Another reason is related to the type of content in array. For example, you are defining a float array and inserting string values in it.

Consider this code example –

import numpy as np
print(np.array([[1, 2], [3, 4, 5]]))

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This will throw valueerror setting array element with sequence, because we are asking numpy to create an array from the list which has elements of different dimensions – [1,2] and [3,4,5].

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