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Let me talk about Power Center vs Cloud (IICS), as rest of your future architecture is same except these two technologies. Each of these technologies have their own pros and cons

PowerCenter:

You may have already know most of the capability which PowerCenter offers, one of the main reason to consider moving to PowerCenter is maintenance, you should have a dedicated Administrators to install the product and do the maintenance work on a daily basis., you should use your own infrastructure , database software’s , file storage etc. And you should also plan for upgrades whenever Informatica announces end of life for a certain version.
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Depending on your environment, you may have jobs which process data form Real time loads, Mainframe CDC jobs , Web services , unstructured data processing, flat files and Relational tables, which may slow your environment and some times even after spending months and months with Informatica support you may not get any resolution for the slowness, you need to then plan your scheduling based on the Jobs which use high CPU I/O and during off peaks hours etc.

Additionally,

You also need to procure license based on the edition, irrespective of whether you use a certain feature
You can also enable versioning, to revert to the previous versions in case of any issues during deployment

Cloud:

The major thing to consider when considering cloud is you will get rid of daily maintenance, server patches, upgrades etc. But the real story starts now, there is lot of limitation in terms of development example

• You can’t use any tables in SQL transformation
• You can’t use Lookup transformation if the column name has space
• When connecting ports in web service consumer, if you need to pass a default value to 10 columns, you need to create 10 columns with same default ports and then only connect to 10 ports
• You can’t run your jobs on the cloud, if your web service requests exceed a certain threshold (less than 1 MB, I have to check on the exact number)
• If you change the port name which is used in a variable or transformation, the whole mapping will be invalidated.Learn more from Informatica training

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